Site-specific incorporation of diamondoids on DNA using click chemistry.
نویسندگان
چکیده
A simple and robust solid phase synthetic method for the ligation of diamondoids on the phosphate backbone of DNA with "click" chemistry using [Cu(CH(3)CN)(4)]PF(6) without a stabilizing ligand is reported. It was found that as the size of dimondoid increased, a corresponding increase in melting temperature was observed.
منابع مشابه
Diamondoids and DNA Nanotechnologies
Diamondoids are cage-like saturated hydrocarbons consisting of fused cyclohexane rings. The Diamondoids family of compounds is one of the best candidates for molecular building blocks (MBBs) in nanotechnology to construct organic nanostructures compared to other MBBs known so far. The challenge is to find a route for self-assembly of these cage hydrocarbons and their applications in the bottom-...
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عنوان ژورنال:
- Chemical communications
دوره 48 14 شماره
صفحات -
تاریخ انتشار 2012